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Prior knowledge driven Granger causality analysis on gene regulatory network discovery

BACKGROUND: Our study focuses on discovering gene regulatory networks from time series gene expression data using the Granger causality (GC) model. However, the number of available time points (T) usually is much smaller than the number of target genes (n) in biological datasets. The widely applied...

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Detalles Bibliográficos
Autores principales: Yao, Shun, Yoo, Shinjae, Yu, Dantong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551367/
https://www.ncbi.nlm.nih.gov/pubmed/26316173
http://dx.doi.org/10.1186/s12859-015-0710-1