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HUMAN DEFINITIVE HAEMOGENIC ENDOTHELIUM AND ARTERIAL VASCULAR ENDOTHELIUM REPRESENT DISTINCT LINEAGES

The generation of haematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) will depend on the accurate recapitulation of embryonic haematopoiesis. In the early embryo, HSCs develop from the haemogenic endothelium (HE) and are specified in a Notch-dependent manner through a process...

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Detalles Bibliográficos
Autores principales: Ditadi, Andrea, Sturgeon, Christopher M., Tober, Joanna, Awong, Geneve, Kennedy, Marion, Phillips, Amanda, Azzola, Lisa, Ng, Elizabeth S., Stanley, Edouard, French, Deborah L., Cheng, Xin, Gadue, Paul, Speck, Nancy, Elefanty, Andrew G., Keller, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551438/
https://www.ncbi.nlm.nih.gov/pubmed/25915127
http://dx.doi.org/10.1038/ncb3161