Acetylcholine Acts through Nicotinic Receptors to Enhance the Firing Rate of a Subset of Hypocretin Neurons in the Mouse Hypothalamus through Distinct Presynaptic and Postsynaptic Mechanisms1,2

Hypocretin/orexin neurons regulate many behavioral functions, including addiction. Nicotine acts through nicotinic acetylcholine receptors (nAChRs) to alter firing rate of neurons throughout the brain, leading to addiction-related behaviors. While nAChRs are expressed in the hypothalamus and choline...

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Detalles Bibliográficos
Autores principales: Zhou, Wen-Liang, Gao, Xiao-Bing, Picciotto, Marina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2015
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551500/
https://www.ncbi.nlm.nih.gov/pubmed/26322330
http://dx.doi.org/10.1523/ENEURO.0052-14.2015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551500/
https://www.ncbi.nlm.nih.gov/pubmed/26322330
http://dx.doi.org/10.1523/ENEURO.0052-14.2015

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