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Protection by beta-Hydroxybutyric acid against insulin glycation, lipid peroxidation and microglial cell apoptosis

BACKGROUND: Diabetes mellitus is characterized jointly by hyperglycemia and hyperinsulinemia that make insulin more prone to be glycated and evolve insulin advanced glycation end products (Insulin- AGE). Here, we report the effect of beta-hydroxy butyrate (BHB) (the predominant ketone body) on the f...

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Detalles Bibliográficos
Autores principales:	Sabokdast, Manijheh, Habibi-Rezaei, Mehran, Moosavi-Movahedi, Ali Akbar, Ferdousi, Maryam, Azimzadeh-Irani, Effat, Poursasan, Najmeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551523/ https://www.ncbi.nlm.nih.gov/pubmed/26311627 http://dx.doi.org/10.1186/s40199-015-0126-5

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