Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing

The development of novel affinity probes for cancer biomarkers may enable powerful improvements in analytical methods for detecting and treating cancer. In this report, we describe our use of capillary electrophoresis (CE) as the separation mechanism in the process of selecting DNA aptamers with aff...

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Detalles Bibliográficos
Autores principales: Eaton, Rachel M., Shallcross, Jamie A., Mael, Liora E., Mears, Kepler S., Minkoff, Lisa, Scoville, Delia J., Whelan, Rebecca J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551533/
https://www.ncbi.nlm.nih.gov/pubmed/25863801
http://dx.doi.org/10.1007/s00216-015-8665-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551533/
https://www.ncbi.nlm.nih.gov/pubmed/25863801
http://dx.doi.org/10.1007/s00216-015-8665-7

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