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Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing
The development of novel affinity probes for cancer biomarkers may enable powerful improvements in analytical methods for detecting and treating cancer. In this report, we describe our use of capillary electrophoresis (CE) as the separation mechanism in the process of selecting DNA aptamers with aff...
Autores principales: | Eaton, Rachel M., Shallcross, Jamie A., Mael, Liora E., Mears, Kepler S., Minkoff, Lisa, Scoville, Delia J., Whelan, Rebecca J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551533/ https://www.ncbi.nlm.nih.gov/pubmed/25863801 http://dx.doi.org/10.1007/s00216-015-8665-7 |
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