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Translational biomarkers of acetaminophen-induced acute liver injury

Acetaminophen (APAP) is a commonly used analgesic drug that can cause liver injury, liver necrosis and liver failure. APAP-induced liver injury is associated with glutathione depletion, the formation of APAP protein adducts, the generation of reactive oxygen and nitrogen species and mitochondrial in...

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Detalles Bibliográficos
Autores principales: Beger, Richard D., Bhattacharyya, Sudeepa, Yang, Xi, Gill, Pritmohinder S., Schnackenberg, Laura K., Sun, Jinchun, James, Laura P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551536/
https://www.ncbi.nlm.nih.gov/pubmed/25983262
http://dx.doi.org/10.1007/s00204-015-1519-4