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Translational biomarkers of acetaminophen-induced acute liver injury
Acetaminophen (APAP) is a commonly used analgesic drug that can cause liver injury, liver necrosis and liver failure. APAP-induced liver injury is associated with glutathione depletion, the formation of APAP protein adducts, the generation of reactive oxygen and nitrogen species and mitochondrial in...
Autores principales: | Beger, Richard D., Bhattacharyya, Sudeepa, Yang, Xi, Gill, Pritmohinder S., Schnackenberg, Laura K., Sun, Jinchun, James, Laura P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551536/ https://www.ncbi.nlm.nih.gov/pubmed/25983262 http://dx.doi.org/10.1007/s00204-015-1519-4 |
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