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Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid/N-acylethanolamine-dependent mechanisms

BACKGROUND: Fatty acid binding proteins (FABPs) serve as intracellular carriers that deliver endocannabinoids and N-acylethanolamines to their catabolic enzymes. Inhibition of FABPs reduces endocannabinoid transport and catabolism in cells and FABP inhibitors produce antinociceptive and anti-inflamm...

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Detalles Bibliográficos
Autores principales: Kaczocha, Martin, Glaser, Sherrye T., Maher, Thomas, Clavin, Brendan, Hamilton, John, O’Rourke, Joseph, Rebecchi, Mario, Puopolo, Michelino, Owada, Yuji, Thanos, Panayotis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551694/
https://www.ncbi.nlm.nih.gov/pubmed/26311517
http://dx.doi.org/10.1186/s12990-015-0056-8