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Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid/N-acylethanolamine-dependent mechanisms
BACKGROUND: Fatty acid binding proteins (FABPs) serve as intracellular carriers that deliver endocannabinoids and N-acylethanolamines to their catabolic enzymes. Inhibition of FABPs reduces endocannabinoid transport and catabolism in cells and FABP inhibitors produce antinociceptive and anti-inflamm...
Autores principales: | Kaczocha, Martin, Glaser, Sherrye T., Maher, Thomas, Clavin, Brendan, Hamilton, John, O’Rourke, Joseph, Rebecchi, Mario, Puopolo, Michelino, Owada, Yuji, Thanos, Panayotis K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551694/ https://www.ncbi.nlm.nih.gov/pubmed/26311517 http://dx.doi.org/10.1186/s12990-015-0056-8 |
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