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Proteomic profiling identifies specific histone species associated with leukemic and cancer cells

BACKGROUND: Chromatin is an extraordinarily complex structure. Much of this complexity results from the presence of numerous histone post-translational modifications and histone variants. Alterations in the patterns of histone post-translational modifications are emerging as a feature of many types...

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Detalles Bibliográficos
Autores principales: Singh, Rajbir, Harshman, Sean W., Ruppert, Amy S., Mortazavi, Amir, Lucas, David M., Thomas-Ahner, Jennifer M., Clinton, Steven K., Byrd, John C., Freitas, Michael A., Parthun, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551702/
https://www.ncbi.nlm.nih.gov/pubmed/26321891
http://dx.doi.org/10.1186/s12014-015-9095-4