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Enhanced chemokine-receptor expression, function, and signaling in healthy African American and scleroderma-patient monocytes are regulated by caveolin-1

BACKGROUND: A major health disparity suffered by African Americans (AA) is a predisposition toward fibrotic diseases of the skin, lung, and other organs. We previously showed that healthy AA and scleroderma (systemic sclerosis (SSc)) patient monocytes share biochemical and functional differences fro...

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Detalles Bibliográficos
Autores principales: Lee, Rebecca, Reese, Charles, Perry, Beth, Heywood, Jonathan, Bonner, Michael, Zemskova, Marina, Silver, Richard M., Hoffman, Stanley, Tourkina, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551709/
https://www.ncbi.nlm.nih.gov/pubmed/26322128
http://dx.doi.org/10.1186/s13069-015-0028-7