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Breaching the Castle Walls: Hyaluronan Depletion as a Therapeutic Approach to Cancer Therapy
Hyaluronan (HA) has many functions in the extracellular milieu of normal and diseased tissues. Disease-associated HA accumulation has been shown to predict a worsened prognosis in cancer patients, with tumors having a high-extracellular HA content (HA-high) being more aggressive than their HA-low co...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551830/ https://www.ncbi.nlm.nih.gov/pubmed/26380222 http://dx.doi.org/10.3389/fonc.2015.00192 |