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Different Mechanisms of Regulation of the Warburg Effect in Lymphoblastoid and Burkitt Lymphoma Cells

BACKGROUND: The Warburg effect is one of the hallmarks of cancer and rapidly proliferating cells. It is known that the hypoxia-inducible factor 1-alpha (HIF1A) and MYC proteins cooperatively regulate expression of the HK2 and PDK1 genes, respectively, in the Burkitt lymphoma (BL) cell line P493-6, c...

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Detalles Bibliográficos
Autores principales: Mushtaq, Muhammad, Darekar, Suhas, Klein, George, Kashuba, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551852/
https://www.ncbi.nlm.nih.gov/pubmed/26312753
http://dx.doi.org/10.1371/journal.pone.0136142