Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT

Telomerase is the enzyme that maintains the length of telomeres. It is minimally constituted of two components: a core reverse transcriptase protein (hTERT) and an RNA (hTR). Despite its significance as an almost universal cancer target, the understanding of the structure of telomerase and the optim...

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Detalles Bibliográficos
Autores principales: Kellermann, Guillaume, Kaiser, Markus, Dingli, Florent, Lahuna, Olivier, Naud-Martin, Delphine, Mahuteau-Betzer, Florence, Loew, Damarys, Ségal-Bendirdjian, Evelyne, Teulade-Fichou, Marie-Paule, Bombard, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551907/
https://www.ncbi.nlm.nih.gov/pubmed/25958399
http://dx.doi.org/10.1093/nar/gkv425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551907/
https://www.ncbi.nlm.nih.gov/pubmed/25958399
http://dx.doi.org/10.1093/nar/gkv425

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