Nucleic acid-binding specificity of human FUS protein

FUS, a nuclear RNA-binding protein, plays multiple roles in RNA processing. Five specific FUS-binding RNA sequence/structure motifs have been proposed, but their affinities for FUS have not been directly compared. Here we find that human FUS binds all these sequences with K(d)(app) values spanning a...

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Detalles Bibliográficos
Autores principales: Wang, Xueyin, Schwartz, Jacob C., Cech, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551922/
https://www.ncbi.nlm.nih.gov/pubmed/26150427
http://dx.doi.org/10.1093/nar/gkv679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551922/
https://www.ncbi.nlm.nih.gov/pubmed/26150427
http://dx.doi.org/10.1093/nar/gkv679

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