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Generation of supercoils in nicked and gapped DNA drives DNA unknotting and postreplicative decatenation
Due to the helical structure of DNA the process of DNA replication is topologically complex. Freshly replicated DNA molecules are catenated with each other and are frequently knotted. For proper functioning of DNA it is necessary to remove all of these entanglements. This is done by DNA topoisomeras...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551925/ https://www.ncbi.nlm.nih.gov/pubmed/26150424 http://dx.doi.org/10.1093/nar/gkv683 |