Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes

Cations are known to mediate diverse interactions in nucleic acids duplexes but they are critical in the arrangement of four-stranded structures. Here, we use all-atom molecular dynamics simulations with explicit solvent to analyse the mechanical unfolding of representative intramolecular G-quadrupl...

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Detalles Bibliográficos
Autores principales: Bergues-Pupo, Ana Elisa, Arias-Gonzalez, J. Ricardo, Morón, María Carmen, Fiasconaro, Alessandro, Falo, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551928/
https://www.ncbi.nlm.nih.gov/pubmed/26170233
http://dx.doi.org/10.1093/nar/gkv690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551928/
https://www.ncbi.nlm.nih.gov/pubmed/26170233
http://dx.doi.org/10.1093/nar/gkv690

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