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Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes
Cations are known to mediate diverse interactions in nucleic acids duplexes but they are critical in the arrangement of four-stranded structures. Here, we use all-atom molecular dynamics simulations with explicit solvent to analyse the mechanical unfolding of representative intramolecular G-quadrupl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551928/ https://www.ncbi.nlm.nih.gov/pubmed/26170233 http://dx.doi.org/10.1093/nar/gkv690 |