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EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele

The maintenance of genome stability is critical for the suppression of diverse human pathologies that include developmental disorders, premature aging, infertility and predisposition to cancer. The DNA damage response (DDR) orchestrates the appropriate cellular responses following the detection of l...

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Detalles Bibliográficos
Autores principales: Rein, Katrin, Yanez, Diana A., Terré, Berta, Palenzuela, Lluís, Aivio, Suvi, Wei, Kaichun, Edelmann, Winfried, Stark, Jeremy M., Stracker, Travis H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551929/
https://www.ncbi.nlm.nih.gov/pubmed/26160886
http://dx.doi.org/10.1093/nar/gkv691