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EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele
The maintenance of genome stability is critical for the suppression of diverse human pathologies that include developmental disorders, premature aging, infertility and predisposition to cancer. The DNA damage response (DDR) orchestrates the appropriate cellular responses following the detection of l...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551929/ https://www.ncbi.nlm.nih.gov/pubmed/26160886 http://dx.doi.org/10.1093/nar/gkv691 |