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Improved prediction of RNA secondary structure by integrating the free energy model with restraints derived from experimental probing data

Recently, several experimental techniques have emerged for probing RNA structures based on high-throughput sequencing. However, most secondary structure prediction tools that incorporate probing data are designed and optimized for particular types of experiments. For example, RNAstructure-Fold is op...

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Detalles Bibliográficos
Autores principales: Wu, Yang, Shi, Binbin, Ding, Xinqiang, Liu, Tong, Hu, Xihao, Yip, Kevin Y., Yang, Zheng Rong, Mathews, David H., Lu, Zhi John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551937/
https://www.ncbi.nlm.nih.gov/pubmed/26170232
http://dx.doi.org/10.1093/nar/gkv706