Accurate placement of substrate RNA by Gar1 in H/ACA RNA-guided pseudouridylation

H/ACA RNA-guided ribonucleoprotein particle (RNP), the most complicated RNA pseudouridylase so far known, uses H/ACA guide RNA for substrate capture and four proteins (Cbf5, Nop10, L7Ae and Gar1) for pseudouridylation. Although it was shown that Gar1 not only facilitates the product release, but als...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Yang, Lijiang, Gao, Yi Qin, Zhao, Xin Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551948/
https://www.ncbi.nlm.nih.gov/pubmed/26206671
http://dx.doi.org/10.1093/nar/gkv757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551948/
https://www.ncbi.nlm.nih.gov/pubmed/26206671
http://dx.doi.org/10.1093/nar/gkv757

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