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Solution structure of the transmembrane domain of the mouse erythropoietin receptor in detergent micelles

Erythropoiesis is regulated by the erythropoietin receptor (EpoR) binding to its ligand. The transmembrane domain (TMD) and the juxtamembrane (JM) regions of the EpoR are important for signal transduction across the cell membrane. We report a solution NMR study of the mouse erythropoietin receptor (...

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Detalles Bibliográficos
Autores principales: Li, Qingxin, Lei Wong, Ying, Yueqi Lee, Michelle, Li, Yan, Kang, CongBao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551963/
https://www.ncbi.nlm.nih.gov/pubmed/26316120
http://dx.doi.org/10.1038/srep13586