High Affinity Binders to EphA2 Isolated from Abdurin Scaffold Libraries; Characterization, Binding and Tumor Targeting

Abdurins are a novel antibody-like scaffold derived from the engineering of a single isolated CH2 domain of human IgG. Previous studies established the prolonged serum half-life of Abdurins, the result of a retained FcRn binding motif. Here we present data on the construction of large, diverse, phag...

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Detalles Bibliográficos
Autores principales: Ullman, Christopher, Mathonet, Pascale, Oleksy, Arkadiusz, Diamandakis, Agata, Tomei, Licia, Demartis, Anna, Nardi, Chiara, Sambucini, Sonia, Missineo, Antonino, Alt, Karen, Hagemeyer, Christoph E., Harris, Matt, Hedt, Amos, Weis, Roland, Gehlsen, Kurt R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552014/
https://www.ncbi.nlm.nih.gov/pubmed/26313909
http://dx.doi.org/10.1371/journal.pone.0135278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552014/
https://www.ncbi.nlm.nih.gov/pubmed/26313909
http://dx.doi.org/10.1371/journal.pone.0135278

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