KLF4 Dependent Phenotypic Modulation of SMCs Plays a Key Role in Atherosclerotic Plaque Pathogenesis

Herein we employ Myh11-CreER(T2) ROSA floxed STOP eYFP Apoe(−/−) smooth muscle cell (SMC) lineage tracing mice to show that traditional methods for detecting SMCs based on immuno-staining fail to detect > 80% of SMC-derived cells within advanced atherosclerotic lesions. These unidentified SMC-der...

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Detalles Bibliográficos
Autores principales: Shankman, Laura S., Gomez, Delphine, Cherepanova, Olga A., Salmon, Morgan, Alencar, Gabriel F., Haskins, Ryan M., Swiatlowska, Pamela, Newman, Alexandra A. C., Greene, Elizabeth S., Straub, Adam C., Isakson, Brant, Randolph, Gwendalyn J., Owens, Gary K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552085/
https://www.ncbi.nlm.nih.gov/pubmed/25985364
http://dx.doi.org/10.1038/nm.3866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552085/
https://www.ncbi.nlm.nih.gov/pubmed/25985364
http://dx.doi.org/10.1038/nm.3866

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