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Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil Recruitment

An important determinant of disease following Streptococcus pneumoniae (pneumococcus) lung infection is pulmonary inflammation mediated by polymorphonuclear leukocytes (PMNs). We found that upon intratracheal challenge of mice, recruitment of PMNs into the lungs within the first 3 hours coincided wi...

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Detalles Bibliográficos
Autores principales: Bou Ghanem, Elsa N., Clark, Stacie, Roggensack, Sara E., McIver, Sally R., Alcaide, Pilar, Haydon, Philip G., Leong, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552087/
https://www.ncbi.nlm.nih.gov/pubmed/26313746
http://dx.doi.org/10.1371/journal.ppat.1005126