Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway

BACKGROUND: There is increasing evidence supporting the concept of cancer stem cells (CSCs), which are responsible for the initiation, growth and metastasis of tumors. CSCs are thus considered the target for future cancer therapies. To achieve this goal, identifying potential therapeutic targets for...

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Detalles Bibliográficos
Autores principales: Gu, Wenyi, Prasadam, Indira, Yu, Meihua, Zhang, Fengxia, Ling, Patrick, Xiao, Yin, Yu, Chengzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552156/
https://www.ncbi.nlm.nih.gov/pubmed/26315028
http://dx.doi.org/10.1186/s12885-015-1614-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552156/
https://www.ncbi.nlm.nih.gov/pubmed/26315028
http://dx.doi.org/10.1186/s12885-015-1614-1

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