A framework for the in vitro evaluation of cancer-relevant molecular characteristics and mitogenic potency of insulin analogues

Epidemiological and laboratory studies raise the possibility of a link between clinically prescribed insulin analogues and increased cancer risk. Accordingly, there is a regulatory mandate for cancer-related pre-clinical safety evaluation during insulin analogue development, but currently, there is...

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Detalles Bibliográficos
Autores principales: Baricevic, Ivona, Jones, David R., Roberts, Darren L., Lutzen, Anne, Lundby, Anders, Worm, Jesper, Hansen, Bo F., Renehan, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Manuscript
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552242/
https://www.ncbi.nlm.nih.gov/pubmed/26026165
http://dx.doi.org/10.1093/carcin/bgv071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552242/
https://www.ncbi.nlm.nih.gov/pubmed/26026165
http://dx.doi.org/10.1093/carcin/bgv071

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