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A framework for the in vitro evaluation of cancer-relevant molecular characteristics and mitogenic potency of insulin analogues
Epidemiological and laboratory studies raise the possibility of a link between clinically prescribed insulin analogues and increased cancer risk. Accordingly, there is a regulatory mandate for cancer-related pre-clinical safety evaluation during insulin analogue development, but currently, there is...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552242/ https://www.ncbi.nlm.nih.gov/pubmed/26026165 http://dx.doi.org/10.1093/carcin/bgv071 |