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IGF-1 in Friedreich’s Ataxia – proof-of-concept trial
BACKGROUND: Friedreich’s ataxia is an autosomal recessive, severely incapacitating disorder. There is little objective evidence regarding FRDA management. Abnormalities in the insulin/insulin-like growth factor 1 (IGF-1) system (IIS) signalling pathway were thought to play a role in the physiopathol...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552279/ https://www.ncbi.nlm.nih.gov/pubmed/26331034 http://dx.doi.org/10.1186/2053-8871-1-10 |