IGF-1 in Friedreich’s Ataxia – proof-of-concept trial

BACKGROUND: Friedreich’s ataxia is an autosomal recessive, severely incapacitating disorder. There is little objective evidence regarding FRDA management. Abnormalities in the insulin/insulin-like growth factor 1 (IGF-1) system (IIS) signalling pathway were thought to play a role in the physiopathol...

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Detalles Bibliográficos
Autores principales: Sanz-Gallego, Irene, Torres-Aleman, Ignacio, Arpa, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552279/
https://www.ncbi.nlm.nih.gov/pubmed/26331034
http://dx.doi.org/10.1186/2053-8871-1-10

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