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Alleviating neurodegeneration in Drosophila models of PolyQ diseases

Polyglutamine (polyQ) diseases are a group of neurodegenerative conditions, induced from CAG trinucleotide repeat expansion within causative gene respectively. Generation of toxic proteins, containing polyQ-expanded tract, is the key process to cause neurodegeneration. Till now, although polyQ disea...

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Detalles Bibliográficos
Autores principales: Long, Zhe, Tang, Beisha, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552282/
https://www.ncbi.nlm.nih.gov/pubmed/26331033
http://dx.doi.org/10.1186/2053-8871-1-9