Exploration of hydroxymethylation in Kagami-Ogata syndrome caused by hypermethylation of imprinting control regions

BACKGROUND: 5-Hydroxymethylcytosine (5hmC), converted from 5-methylcytosine (5mC) by ten-eleven translocation (Tet) enzymes, has recently drawn attention as the “sixth base” of DNA since it is considered an intermediate of the demethylation pathway. Nonetheless, it remains to be addressed how 5hmC i...

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Detalles Bibliográficos
Autores principales: Matsubara, Keiko, Kagami, Masayo, Nakabayashi, Kazuhiko, Hata, Kenichiro, Fukami, Maki, Ogata, Tsutomu, Yamazawa, Kazuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552283/
https://www.ncbi.nlm.nih.gov/pubmed/26322139
http://dx.doi.org/10.1186/s13148-015-0124-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552283/
https://www.ncbi.nlm.nih.gov/pubmed/26322139
http://dx.doi.org/10.1186/s13148-015-0124-y

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