Clausmarin A, Potential Immunosuppressant Revealed by Yeast-Based Assay and Interleukin-2 Production Assay in Jurkat T Cells

Small-molecule inhibitors of Ca(2+)-signaling pathways are of medicinal importance, as exemplified by the immunosuppressants FK506 and cyclosporin A. Using a yeast-based assay devised for the specific detection of Ca(2+)-signaling inhibitors, clausmarin A, a previously reported terpenoid coumarin, w...

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Detalles Bibliográficos
Autores principales: Suauam, Pitipreya, Yingyongnarongkul, Boon-ek, Palaga, Tanapat, Miyakawa, Tokichi, Yompakdee, Chulee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552291/
https://www.ncbi.nlm.nih.gov/pubmed/26313553
http://dx.doi.org/10.1371/journal.pone.0136804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552291/
https://www.ncbi.nlm.nih.gov/pubmed/26313553
http://dx.doi.org/10.1371/journal.pone.0136804

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