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Clausmarin A, Potential Immunosuppressant Revealed by Yeast-Based Assay and Interleukin-2 Production Assay in Jurkat T Cells
Small-molecule inhibitors of Ca(2+)-signaling pathways are of medicinal importance, as exemplified by the immunosuppressants FK506 and cyclosporin A. Using a yeast-based assay devised for the specific detection of Ca(2+)-signaling inhibitors, clausmarin A, a previously reported terpenoid coumarin, w...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552291/ https://www.ncbi.nlm.nih.gov/pubmed/26313553 http://dx.doi.org/10.1371/journal.pone.0136804 |