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Intermediate Tyrosyl Radical and Amyloid Structure in Peroxide-Activated Cytoglobin

We characterized the peroxidase mechanism of recombinant rat brain cytoglobin (Cygb) challenged by hydrogen peroxide, tert-butylhydroperoxide and by cumene hydroperoxide. The peroxidase mechanism of Cygb is similar to that of myoglobin. Cygb challenged by hydrogen peroxide is converted to a Fe(4+) o...

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Detalles Bibliográficos
Autores principales: Ferreira, Juliana C., Marcondes, Marcelo F., Icimoto, Marcelo Y., Cardoso, Thyago H. S., Tofanello, Aryane, Pessoto, Felipe S., Miranda, Erica G. A., Prieto, Tatiana, Nascimento, Otaciro R., Oliveira, Vitor, Nantes, Iseli L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552303/
https://www.ncbi.nlm.nih.gov/pubmed/26312997
http://dx.doi.org/10.1371/journal.pone.0136554