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Enzyme-Free Detection of Mutations in Cancer DNA Using Synthetic Oligonucleotide Probes and Fluorescence Microscopy

BACKGROUND: Rapid reliable diagnostics of DNA mutations are highly desirable in research and clinical assays. Current development in this field goes simultaneously in two directions: 1) high-throughput methods, and 2) portable assays. Non-enzymatic approaches are attractive for both types of methods...

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Detalles Bibliográficos
Autores principales: Miotke, Laura, Maity, Arindam, Ji, Hanlee, Brewer, Jonathan, Astakhova, Kira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552304/
https://www.ncbi.nlm.nih.gov/pubmed/26312489
http://dx.doi.org/10.1371/journal.pone.0136720