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Unraveling Comparative Anti-Amyloidogenic Behavior of Pyrazinamide and D-Cycloserine: A Mechanistic Biophysical Insight

Amyloid fibril formation by proteins leads to variety of degenerative disorders called amyloidosis. While these disorders are topic of extensive research, effective treatments are still unavailable. Thus in present study, two anti-tuberculosis drugs, i.e., pyrazinamide (PYZ) and D-cycloserine (DCS),...

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Detalles Bibliográficos
Autores principales: Chaturvedi, Sumit Kumar, Zaidi, Nida, Alam, Parvez, Khan, Javed Masood, Qadeer, Atiyatul, Siddique, Ibrar Ahmad, Asmat, Shamoon, Zaidi, Yusra, Khan, Rizwan Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552381/
https://www.ncbi.nlm.nih.gov/pubmed/26312749
http://dx.doi.org/10.1371/journal.pone.0136528