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Type I Interferons Function as Autocrine and Paracrine Factors to Induce Autotaxin in Response to TLR Activation
Lysophosphatidic acid (LPA) is an important phospholipid mediator in inflammation and immunity. However, the mechanism of LPA regulation during inflammatory response is largely unknown. Autotaxin (ATX) is the key enzyme to produce extracellular LPA from lysophosphatidylcholine (LPC). In this study,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552386/ https://www.ncbi.nlm.nih.gov/pubmed/26313906 http://dx.doi.org/10.1371/journal.pone.0136629 |