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Is the whole greater than the sum of its parts? De novo assembly strategies for bacterial genomes based on paired-end sequencing

BACKGROUND: Whole genome sequence construction is becoming increasingly feasible because of advances in next generation sequencing (NGS), including increasing throughput and read length. By simply overlapping paired-end reads, we can obtain longer reads with higher accuracy, which can facilitate the...

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Detalles Bibliográficos
Autores principales: Chen, Ting-Wen, Gan, Ruei-Chi, Chang, Yi-Feng, Liao, Wei-Chao, Wu, Timothy H., Lee, Chi-Ching, Huang, Po-Jung, Lee, Cheng-Yang, Chen, Yi-Ywan M., Chiu, Cheng-Hsun, Tang, Petrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552406/
https://www.ncbi.nlm.nih.gov/pubmed/26315384
http://dx.doi.org/10.1186/s12864-015-1859-8