Autologous cellular vaccine overcomes cancer immunoediting in a mouse model of myeloma

In the Sp6 mouse plasmacytoma model, a whole-cell vaccination with Sp6 cells expressing de novo B7-1 (Sp6/B7) induced anatomically localized and cytotoxic T cell (CTL) -mediated protection against wild-type (WT) Sp6. Both WT Sp6 and Sp6/B7 showed down-regulated expression of MHC H-2 L(d). Increase o...

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Detalles Bibliográficos
Autores principales: Mazzocco, Marta, Martini, Matteo, Rosato, Antonio, Stefani, Elisabetta, Matucci, Andrea, Dalla Santa, Silvia, De Sanctis, Francesco, Ugel, Stefano, Sandri, Sara, Ferrarini, Giovanna, Cestari, Tiziana, Ferrari, Sergio, Zanovello, Paola, Bronte, Vincenzo, Sartoris, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552499/
https://www.ncbi.nlm.nih.gov/pubmed/25959091
http://dx.doi.org/10.1111/imm.12477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552499/
https://www.ncbi.nlm.nih.gov/pubmed/25959091
http://dx.doi.org/10.1111/imm.12477

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