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Autologous cellular vaccine overcomes cancer immunoediting in a mouse model of myeloma
In the Sp6 mouse plasmacytoma model, a whole-cell vaccination with Sp6 cells expressing de novo B7-1 (Sp6/B7) induced anatomically localized and cytotoxic T cell (CTL) -mediated protection against wild-type (WT) Sp6. Both WT Sp6 and Sp6/B7 showed down-regulated expression of MHC H-2 L(d). Increase o...
Autores principales: | Mazzocco, Marta, Martini, Matteo, Rosato, Antonio, Stefani, Elisabetta, Matucci, Andrea, Dalla Santa, Silvia, De Sanctis, Francesco, Ugel, Stefano, Sandri, Sara, Ferrarini, Giovanna, Cestari, Tiziana, Ferrari, Sergio, Zanovello, Paola, Bronte, Vincenzo, Sartoris, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552499/ https://www.ncbi.nlm.nih.gov/pubmed/25959091 http://dx.doi.org/10.1111/imm.12477 |
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