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Leukotriene D(4)-induced Caco-2 cell proliferation is mediated by prostaglandin E(2) synthesis
Leukotriene D(4) (LTD(4)) is a pro-inflammatory mediator formed from arachidonic acid through the action of 5-lipoxygenase (5-LOX). Its biological effects are mediated by at least two G-coupled plasmatic cysteinyl LT receptors (CysLT(1-2)R). It has been reported an upregulation of the 5-LOX pathway...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552517/ https://www.ncbi.nlm.nih.gov/pubmed/26216432 http://dx.doi.org/10.14814/phy2.12417 |