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Leukotriene D(4)-induced Caco-2 cell proliferation is mediated by prostaglandin E(2) synthesis

Leukotriene D(4) (LTD(4)) is a pro-inflammatory mediator formed from arachidonic acid through the action of 5-lipoxygenase (5-LOX). Its biological effects are mediated by at least two G-coupled plasmatic cysteinyl LT receptors (CysLT(1-2)R). It has been reported an upregulation of the 5-LOX pathway...

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Detalles Bibliográficos
Autores principales: Cabral, Marisol, Martín-Venegas, Raquel, Moreno, Juan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552517/
https://www.ncbi.nlm.nih.gov/pubmed/26216432
http://dx.doi.org/10.14814/phy2.12417

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