Paired Exome Analysis of Barrett’s Esophagus and Adenocarcinoma

Barrett’s esophagus, is thought to progress to esophageal adenocarcinoma (EAC) through a step-wise progression with loss of CDKN2A followed by p53 inactivation and aneuploidy. Here, we present whole exome sequencing from 25 pairs of EAC and Barrett’s and five patients whose Barrett’s and tumor were...

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Detalles Bibliográficos
Autores principales: Stachler, Matthew D., Taylor-Weiner, Amaro, Peng, Shouyong, McKenna, Aaron, Agoston, Agoston T., Odze, Robert D., Davison, Jon M., Nason, Katie S., Loda, Massimo, Leshchiner, Ignaty, Stewart, Chip, Stojanov, Petar, Seepo, Sara, Lawrence, Michael S., Ferrer-Torres, Daysha, Lin, Jules, Chang, Andrew C., Gabriel, Stacey B., Lander, Eric S., Beer, David G., Getz, Gad, Carter, Scott L., Bass, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552571/
https://www.ncbi.nlm.nih.gov/pubmed/26192918
http://dx.doi.org/10.1038/ng.3343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552571/
https://www.ncbi.nlm.nih.gov/pubmed/26192918
http://dx.doi.org/10.1038/ng.3343

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