INF-γ Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself

BACKGROUND: The cytokine and drug interferon-γ enhances superoxide anion production by the antimicrobicidal Nox2 enzyme of neutrophils. Because mature neutrophils have a short lifespan, we hypothesized that the effects of interferon-γ on these cells might be mediated by its prolonged exposure to dif...

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Detalles Bibliográficos
Autores principales: Ellison, Michael A., Thurman, Gail, Gearheart, Christy M., Seewald, Ryan H., Porter, Christopher C., Ambruso, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552644/
https://www.ncbi.nlm.nih.gov/pubmed/26317224
http://dx.doi.org/10.1371/journal.pone.0136766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552644/
https://www.ncbi.nlm.nih.gov/pubmed/26317224
http://dx.doi.org/10.1371/journal.pone.0136766

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