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Targeting the Sonic Hedgehog-Gli1 Pathway as a Potential New Therapeutic Strategy for Myelodysplastic Syndromes

The complex mechanistic array underlying the pathogenesis of myelodysplastic syndrome (MDS) is still unclear. Although dysregulations of different signaling pathways involved in MDS have been described, the identification of specific biomarkers and therapy targets remains an important task in order...

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Detalles Bibliográficos
Autores principales: Zou, Jixue, Zhou, Zhigang, Wan, Liping, Tong, Yin, Qin, Youwen, Wang, Chun, Zhou, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552723/
https://www.ncbi.nlm.nih.gov/pubmed/26317501
http://dx.doi.org/10.1371/journal.pone.0136843