Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue

Streptococcus pneumoniae is a major cause of pneumonia, sepsis and meningitis. The pore-forming toxin pneumolysin is a key virulence factor of S. pneumoniae, which can be sensed by the NLRP3 inflammasome. Among the over 90 serotypes, serotype 1 pneumococci (particularly MLST306) have emerged across...

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Detalles Bibliográficos
Autores principales: Fatykhova, Diana, Rabes, Anne, Machnik, Christoph, Guruprasad, Kunchur, Pache, Florence, Berg, Johanna, Toennies, Mario, Bauer, Torsten T., Schneider, Paul, Schimek, Maria, Eggeling, Stephan, Mitchell, Timothy J., Mitchell, Andrea M., Hilker, Rolf, Hain, Torsten, Suttorp, Norbert, Hippenstiel, Stefan, Hocke, Andreas C., Opitz, Bastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552725/
https://www.ncbi.nlm.nih.gov/pubmed/26317436
http://dx.doi.org/10.1371/journal.pone.0137108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552725/
https://www.ncbi.nlm.nih.gov/pubmed/26317436
http://dx.doi.org/10.1371/journal.pone.0137108

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