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Mitochondrial Activity and Cyr1 Are Key Regulators of Ras1 Activation of C. albicans Virulence Pathways

Candida albicans is both a major fungal pathogen and a member of the commensal human microflora. The morphological switch from yeast to hyphal growth is associated with disease and many environmental factors are known to influence the yeast-to-hyphae switch. The Ras1-Cyr1-PKA pathway is a major regu...

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Detalles Bibliográficos
Autores principales: Grahl, Nora, Demers, Elora G., Lindsay, Allia K., Harty, Colleen E., Willger, Sven D., Piispanen, Amy E., Hogan, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552728/
https://www.ncbi.nlm.nih.gov/pubmed/26317337
http://dx.doi.org/10.1371/journal.ppat.1005133