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Usefulness of Time-Point Serum Cortisol and ACTH Measurements for the Adjustment of Glucocorticoid Replacement in Adrenal Insufficiency

BACKGROUND: Adjustment of daily hydrocortisone dose on clinical criteria lacks sensitivity for fine tuning. Long term hydrocortisone (HC) over-replacement may lead to increased morbidity and mortality in patients with adrenal insufficiency (AI). Biochemical criteria may help detecting over- or under...

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Detalles Bibliográficos
Autores principales: Rousseau, Elise, Joubert, Michael, Trzepla, Géraldine, Parienti, Jean Jacques, Freret, Thomas, Vanthygem, Marie Christine, Desailloud, Rachel, Lefebvre, Hervé, Coquerel, Antoine, Reznik, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552782/
https://www.ncbi.nlm.nih.gov/pubmed/26317782
http://dx.doi.org/10.1371/journal.pone.0135975